Skip to content

Tag Archives: TPR

The Management of Hypertension (Pathophysiologic Basises)


Hypertension is a common diseases and is defined as persistently elevated arterial blood pressure of >= 140/90 mm Hg. Most of patients belong to essential hypertension and a small percentage belong to secondary hypertension for which the most common causes include renal dysfunction resulting from severe chronic kidney disease (CKD) or renovascular disease. Besides, certain […]

Arteriolar Tone and Its Regulation (Local Mechanisms)


I.Arteriolar Tone A.Basal tone B.ANS C.Adrenal Glands D.Local 1.Metabolic substances 2.Endothelial cells secretion 3.Other local chemical influences 4.Transmural pressure (myogenic response) II.Venous Tone A.Basal tone (little) B.ANS C.Adrenal glands D.Internal pressure (recall deltaV/deltaP = C) E.External compression (muscle pump) Because the body's needs are continually changing, the cardiovascular system must continually make adjustments in the diameter […]

Vascular Resistances and Compliance, MAP and Pulse Pressure


Resistances In A Single Organ In an organ, the consecutive vascular segments are arranged in series within an organ. Therefore, the overall vascular resistance of the organ must equal the sum of the resistances of its consecutive vascular segments, Because arterioles have a large vascular resistance in comparison to the other vascular segments (see above), […]