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Tag Archives: Renin

Regulation of Sodium Excretion

25-Jun-16

Percentage of Sodium Reabsorbed The Goals of Regulation The overriding goals of regulating sodium and water excretion are to support the requirements of the cardiovascular system. This is manifested in 3 ways: 1.the kidneys maintain a sufficient ECF volume to fill the vascular space (mean circulatory filling pressure); 2.keep the osmolality of the ECF at a level […]

Control of the Circulating RAAS

23-Jun-16

The activity of the circulating RAAS is governed by the amount of renin secreted by the granular cells of the jg (juxtaglomerular) apparatus. There are 3 major controllers of renin secretion. PS: Look at the RAAS, plasma angiotensinogen is synthesized in the liver and plasma angiotensinogen levels are normally high therefore do not limit the production […]

The Regular of Extracellular Fluids – ADH Secretion and Renin-Angiotensin System

09-Mar-14

The volume of ECF is determined primarily by the total amount of osmotically active solute in the ECF. Excessive loss of Na+┬áin the stools (diarrhea), urine (severe acidosis, adrenal insufficiency), or sweat (heat prostration) decreases ECF volume markedly and eventually leads to shock. The regular of extracellular fluids is based on vasopressin (ADH) and renin-angiotensin […]