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Tag Archives: Insulin

Renal Potassium Reabsorption and Secretion


Percentage of fitered load transported at different locations depending on diet The Importance of Potassium Balance The vast majority of body potassium is freely dissolved in the cytosol of tissue cells and constitutes the major osmotic component of the intracellular fluid (ICF). Only about 2% of total-body potassium is in the extracellular fluid (ECF). This small […]

The Management of Hyperglycemic Crises in Diabetes


Diabetic ketoacidosis (DKA) and the hyperosmolar hyperglycemic state (HHS) are the two most serious acute metabolic complications of diabetes. The triad of uncontrolled hyperglycemia, metabolic acidosis (SAG elevated metabolic acidosis), and increased total body ketone concentration characterizes DKA. HHS is characterized by severe hyperglycemia, hyperosmolality, and dehydration in the absence of significant ketoacidosis. Pathogenesis DKA […]

Use insulin Earlier, not Later, in type 2 diabetes


March 29, 2012 (New Orleans, Louisiana) — Insulin administration has traditionally been one of the last steps in the treatment of type 2 diabetes mellitus (T2DM), but that’s changing, says Jonathan Marquess, PharmD, from the Institute for Wellness and Education Inc in Atlanta, Georgia. He discussed the benefits of early initiation and intensification of insulin […]