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Category Archives: Endocrinology

[Endocrinology] The Agonist-Receptor Interaction and Pharmacodynamics of Thyroid Hormone


Thyroid Hormone Receptors and Cellular Events Thyroid hormone receptors are expressed in virtually all tissues and affect multiple cellular events. The cellular actions of thyroid hormones are mediated by multiple thyroid hormone receptor isoforms derived from 2 distinct genes (alpha and beta) encoding thyroid hormone receptors. The functional significance of the different isoforms has not yet […]

[Endocrinology] The Regulation and Clinical Art of Thyroid Hormones


Thyroid Hormone Synthesis Process The Source Components of Thyroid Hormone Thyroglobulin (Tg), plays an important role in the synthesis and storage of thyroid hormone. Tg is a glycoprotein containing multiple tyrosine residues. It is synthesized in the thyroid follicular epithelial cells and secreted through the apical membrane into the follicular lumen, where it is stored […]