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Monthly Archives: June 2017

Some Critical Notices Should Knowing When Using Warfarin

30-Jun-17

PT/INR and Anticoagulation Status For the vast majority of patients        , monitoring is done using the prothrombin time with international normalized ratio (PT/INR), which reflects the degree of anticoagulation due to depletion of vitamin K-dependent coagulation. However, attention must be paid that the PT/INR in a patient on warfarin may note reflect the total anticoagulation status […]

The Differential Diagnosis of Abnormal Serum Uric Acid Concentration

28-Jun-17

Reference range: 4.0-8.5 mg/dL or 237-506 mmol/L for males >17 years old; 2.7-7.3 mg/dL or 161-434 mmol/L for females >17 years old Uric acid is the metabolic end-product of the purine bases of DNA. In humans, uric acid is not metabolized further and is eliminated unchanged by renal excretion (the net result of filtration, secretion, […]

How to compute the expected 95% CI

22-Jun-17

The Random Sampling Distribution of Means Imagine you have a hat containing 100 cards, numbered from 0 to 99. At random, you take out five cards, record the number written on each one, and find the mean of these five numbers. Then you put the cards back in the hat and draw another random sample, […]

Why the Odds Ratio Can Be Used as an Estimate for Relative Risk in a Case-Control Study

10-Jun-17

The data in a case-control study represent two samples: The cases are drawn from a population of people who have the disease and the controls from a population of people who do not have the disease. The predictor variable (risk factor) is measured, and the results can be summarized in a 2 X 2 table […]