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Monthly Archives: June 2015

Volume of Distribution and Factors Affecting It


Definition The volume of distribution for a drug or the "apparent volume of distribution" does not necessarily refer to any physiologic compartment in the body. It is simply the size of a compartment necessary to account for the total amount of drug in the body if it were present throughout the body at the same […]

Flow Resistance of Vessels in Series and Vessels in Parallel


Any network of resistances, however complex, can always be reduced to a single “equivalent” resistor that relates the total flow through the network to the pressure difference across the network. Of course, one way of finding the overall resistance of a network is to perform an experiment to see how much flow goes through it […]

Basic Concepts in Statistics


Three Kinds of Data There are three types of data, including interval data where some variables are measured on a scale with constant intervals, nominal/categorical data, and ordinal data. For interval data, the absolute difference between two values can always be determined by subtraction. Interval variables include some such as tempterature, blood pressure, height, weight, […]

Something You Should Know About The Laboratory Tests


Laboratory Tests might be the most common exams during a outpatient encounter or in the inpatient setting. However, as a clinician the laboratory is not the all. Rather the results of laboratory tests must be integrated into the more comprehensive judgement which includes not only laboratory tests but also patient history, signs and symptoms, etc. […]

Catheter-Related Blood Stream Infections (Pathogenesis and Diagnosis)


Because patients in ICU are commonly plugged with blood catheters, catheter-related blood stream infection (CRBI) can happen and increase the morbidity, the mortality, and the healthcare cost in those patients. Today we talk about the pathogenesis and diagnosis of catheter-related blood stream infections. Pathogenesis The source of catheter-related bloodstream infections are indicated in the figure […]