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Monthly Archives: June 2013

Anti-infection Prophylaxis in Cancer Patients With Neutropenia (Risk Evaluating and Patient Selection)


Cancer patients, particularly those with hematologic malignancies, usually have neutropenia, both disease-related and treatment-related, which makes those patients in danger of various types of infection. The way to prevent these patients from infection is prophylactic antibiotics uses. In this post we talk about how to manage neutropenia patients with cancer who are afebrile. This post […]

The Management of Myelodysplastic Syndromes (MDS)


The myelodysplastic syndromes (MDS) are a collection of myeloid malignancies characterized by one or more peripheral blood cytopenias. MDS are diagnosed in slightly more than 10,000 people in the United States yearly, for an annual age-adjusted incidence rate of approximately 4.4 to 4.6 cases per 100,000 people.¬†They are more common in men and whites. The […]

Platelet Transfusion for Patients With Cancer (Part Three)


If the patient is transfused with platelet alloimmunization might happen, including alloimmunization due to RhD antigens or non-histocompatibility. And the patient might develop refractoriness to platelet transfusion. RhD Antigen-Induced Alloimmunization Platelets do not express Rh antigens on their surface, but quantity or RBCs in platelet preparations is sufficient to induce Rh sensitization, even in immunosuppressed […]

The Management of Disseminated Intravascular Coagulation (DIC)


Disseminated intravascular coagulation (DIC) is characterized by systemic activation of blood coagulation, which results in generation and deposition of fibrin, leading to microvascular thrombi in various organs and contributing to multiple organ dysfunction syndrome (MODS). Consumption and subsequent exhaustion of coagulation proteins and platelets may induce severe bleeding. The International Society on Thrombosis and Haemostasis […]

The Management of Acquired Aplastic Anemia (Strategies)


Aplastic anemia¬†is a disease in which the bone marrow, and the blood stem cells that reside there, are damaged. This causes a deficiency of all three blood cell types (pancytopenia): red blood cells (anemia), white blood cells (leukopenia), and platelets (thrombocytopenia). Until the 1970s, severe aplastic anemia (SAA) was almost uniformly fata, but in the […]