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Monthly Archives: December 2012

Thrombotic Thrombocytopenic Purpura and Its Management


Thrombotic thrombocytopenic purpura (TTP) is the common name for adults with microangiopathic hemolytic anemia, thrombocytopenia, with or without neurologic or renal abnormalities, and without another etiology for thrombotic microangiopathy (TMA). In 10 years before, we believed that the classic clinical features of TTP which was called “classic pentad” were thrombocytopenia, microangiopathic hemolytic anemia, neurologic abnormalities, […]

Angiogenesis: A Target in Leukemia?


VEGF is an important pathway in cancer treatment. In many solid tumor VEGF is a target of anti-tumor agents. VEGF is correlated with the agiogenesis, proliferation, migration, and survival of tumor cells. Functional blood vessels provide the basis of tissue homeostasis and growth with the supply of oxygen and nutrients and the elimination of metabolic […]